Enlivexs Immunotherapy Product Candidate, Allocetra Receives US Patent To Treat Gout, Inflammatory Bowel Disease, Crohns Disease & Ulcerative Colitis
Enlivex Therapeutics, a clinical-stage immunotherapy company, announced that the US Patent and Trademark Office issued a notice of allowance for a new patent application covering methods of using Allocetra, the company’s immunotherapy product candidate. Upon issuance, the new patent will provide added intellectual property protection for methods of treating autoimmune and inflammatory diseases comprising gout, inflammatory bowel disease, Crohn’s disease, and ulcerative colitis. The company expects that this new patent will be issued in the United States in the coming months.Oren Hershkovitz, Ph.D., CEO of Enlivex, stated: “We are pleased with the allowance of this patent application. While we are focusing our clinical development efforts at this stage on life-threatening diseases with high mortality rates and no effective treatments, pre-clinical data have demonstrated the potential applicability of Allocetra in providing immune rebalancing for patients with autoimmune or inflammatory diseases with unmet needs, such as Crohn’s Disease.”Allocetra has been designed to provide a novel immunotherapy mechanism of action that targets life-threatening clinical indications that are defined as “unmet medical needs”, including organ dysfunction and acute multiple organ failure associated with Sepsis and COVID-19, as well as treating solid tumors by modulating such tumors’ microenvironments. In preclinical models, a positive effect of Allocetra was observed in several autoimmune and inflammatory diseases

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