Pfizer announces positive results from phase 3 TALAPRO-2 study of Talzenna in combo with Xtandi to treat mCRPC
Pfizer announced positive results from the phase 3 TALAPRO-2 study of Talzenna (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with Xtandi (enzalutamide), demonstrating a statistically significant and clinically meaningful improvement in radiographic progression-free survival (rPFS) compared to placebo plus Xtandi in men with metastatic castration-resistant prostate cancer (mCRPC), with or without homologous recombination repair (HRR) gene mutations. In addition, the US Food and Drug Administration (FDA) has granted Priority Review for Pfizer
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