Wuxi Biologics And Aravive Form Strategic Collaboration

Wuxi Biologics, A Global Company With Leading Open-Access Biologics Technology Platforms, And Aravive, Inc. (Nasdaq:Arav), A Clinical-Stage Biopharmaceutical Company, Today Announced A Strategic Collaboration Agreement Granting Aravive The Right To Use The Proprietary Wuxibody&Trade; Platform To Develop High-Affinity Bispecific Antibodies For A Target Implicated In Cancer And Fibrosis.Wuxi Biologics And Aravive Will Collaborate To Discover Antibodies Against Ccn2, A Multidomain Protein Also Known As Connective Tissue Growth Factor (Ctgf). Ccn2 Was Identified From A Similar Target Discovery Screen That Identified The Significance Of The Axl/Gas6 Pathway In Cancer. Preclinical Data Identified Ccn2 As Important For Tumor Growth And Progression. Wuxi Biologics Will Be Responsible For Biologics Discovery, Process Development, And Manufacturing. Aravive Will Be Responsible For Preclinical And Clinical Development. The Companies Did Not Disclose The Financial Terms Of The Collaboration. "Aravive'S Proficiency In Development Of Anti-Cancer And Fibrotic Drugs And Wuxi Biologics' Expertise With Biological Discovery And Manufacturing Is A Powerful Combination," Said Gail Mcintyre, Ph.D., Chief Executive Officer Of Aravive. "We Look Forward To Further Expanding Our Collaboration To Identify High Affinity Antibodies That Can Be Exploited As Anti-Cancer And Anti-Fibrotic Agents."In 2018, And Following The Successful Filing Of A U.S. Investigational New Drug Application (Ind) For Avb-500, Wuxi Biologics And Aravive Announced Expansion Of Their Biologics Manufacturing Collaboration Based On The Rapid Success Achieved In The Process Development, Scale-Up And Cgmp Manufacture Of Aravive'S Lead Drug Candidate, Avb-500. "We Are Glad To Once Again Collaborate With Aravive As A Trusted Partner To Accelerate The Discovery, Development And Manufacturing Of Biologics Through Our Innovative Technology Platforms," Said Chris Chen, Ph.D., Chief Executive Officer Of Wuxi Biologics. "Wuxi Biologics' Proprietary Antibody Platforms Including Wuxibody&Trade;, Are Uniquely Positioned To Expedite Development Of Novel Bispecifics To Benefit Global Patients."

Optimize Your trial insights with Clival Database.

Are you exhausted from the uncertainty of trial insights pricing? Clival Database ensures the clarity in the midst of the global scenario for clinical trials to you.

Clival Database is one of the best databases that offers an outstanding number of clinical trial data in terms of 50,000+ molecules and from primary regulatory markets as well as new entrants like Indian and Chinese markets.

With Clival, you get accurate positioning of historical sales data, patent database, company profiling, safety & efficacy, and prediction of launch of new innovative molecules helping you to align your research and driving down the cost.

To add value, we further break down our analytics for you so that improving your operational effectiveness; optimizing your clinical trials; and offering you accurate and high-quality data at lowest possible prices becomes possible.

Elevate your trial success rate with the cutting-edge insights from Clival database.

Check it out today and make more informed sourcing decisions! Learn More!