Bayer rivaroxaban receives Japanese approval to treat patients with PAD after revascularisation
The Ministry of Health, Labour and Welfare in Japan has approved the use of the oral Factor Xa inhibitor rivaroxaban (Xarelto) (2.5 mg twice daily, used in combination with aspirin 81-100 mg once daily) to treat patients with peripheral artery disease (PAD) after revascularization. The approval is based on data from the phase III VOYAGER PAD trial. This study demonstrated a positive benefit-risk profile of starting Xarelto in combination with aspirin in patients with symptomatic PAD after a recent lower-extremity revascularization. It
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